L\u1eddi gi\u1ea3i:<\/strong><\/p>\n– Kh\u00e1i ni\u1ec7m \u0111\u1ed9t bi\u1ebfn gen: \u0110\u1ed9t bi\u1ebfn gen l\u00e0 nh\u1eefng bi\u1ebfn \u0111\u1ed5i trong c\u1ea5u tr\u00fac c\u1ee7a gen, c\u00f3 li\u00ean quan \u0111\u1ebfn m\u1ed9t ho\u1eb7c m\u1ed9t s\u1ed1 c\u1eb7p nucleotit.<\/p>\n
– C\u00e1c d\u1ea1ng \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m:<\/p>\n
* \u0110\u1ed9t bi\u1ebfn thay th\u1ebf m\u1ed9t c\u1eb7p nucleotit<\/p>\n
M\u1ed9t c\u1eb7p nucleotit trong gen khi \u0111\u01b0\u1ee3c thay th\u1ebf b\u1eb1ng m\u1ed9t c\u1eb7p nucleotit kh\u00e1c c\u00f3 th\u1ec3 l\u00e0m thay \u0111\u1ed5i tr\u00ecnh t\u1ef1 axit trong protein v\u00e0 l\u00e0m thay \u0111\u1ed5i ch\u1ee9c n\u0103ng c\u1ee7a protein.<\/p>\n
* \u0110\u1ed9t bi\u1ebfn th\u00eam hay m\u1ea5t m\u1ed9t c\u1eb7p nucleotit<\/p>\n
Khi \u0111\u1ed9t bi\u1ebfn l\u00e0m m\u1ea5t \u0111i hay th\u00eam v\u00e0o m\u1ed9t c\u1eb7p nucleotit trong gen s\u1ebd d\u1eabn \u0111\u1ebfn m\u00e3 di truy\u1ec1n b\u1ecb \u0111\u1ecdc sai k\u1ec3 t\u1eeb v\u1ecb tr\u00ed x\u1ea3y ra \u0111\u1ed9t bi\u1ebfn d\u1eabn \u0111\u1ebfn l\u00e0m thay \u0111\u1ed5i tr\u00ecnh t\u1ef1 axit amin trong chu\u1ed7i polipeptit v\u00e0 l\u00e0m thay \u0111\u1ed5i ch\u1ee9c n\u0103ng c\u1ee7a protein.<\/p>\n
– H\u1eadu qu\u1ea3 c\u1ee7a \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m: \u0111\u1ed9t bi\u1ebfn gen c\u00f3 th\u1ec3 g\u00e2y h\u1ea1i, c\u00f3 l\u1ee3i ho\u1eb7c trung t\u00ednh. M\u1ee9c \u0111\u1ed9 c\u00f3 h\u1ea1i hay c\u00f3 l\u1ee3i c\u1ee7a gen \u0111\u1ed9t bi\u1ebfn ph\u1ee5 thu\u1ed9c v\u00e0o \u0111i\u1ec1u ki\u1ec7n m\u00f4i tr\u01b0\u1eddng c\u0169ng nh\u01b0 t\u00f9y thu\u1ed9c v\u00e0o t\u1ed5 h\u1ee3p gen.<\/p>\n
B\u00e0i 2 (trang 22 SGK Sinh h\u1ecdc 12):\u00a0N\u00eau m\u1ed9t s\u1ed1 c\u01a1 ch\u1ebf ph\u00e1t sinh \u0111\u1ed9t bi\u1ebfn gen.<\/strong><\/p>\nL\u1eddi gi\u1ea3i:<\/b><\/p>\n
M\u1ed9t s\u1ed1 c\u01a1 ch\u1ebf ph\u00e1t sinh \u0111\u1ed9t bi\u1ebfn gen.<\/p>\n
* S\u1ef1 k\u1ebft c\u1eb7p kh\u00f4ng \u0111\u00fang trong t\u00e1i b\u1ea3n ADN<\/p>\n
C\u00e1c baz\u01a1 nit\u01a1 th\u01b0\u1eddng t\u1ed3n t\u1ea1i hai d\u1ea1ng c\u1ea5u tr\u00fac (d\u1ea1ng th\u01b0\u1eddng v\u00e0 d\u1ea1ng hi\u1ebfm). C\u00e1c d\u1ea1ng hi\u1ebfm (h\u1ed7 bi\u1ebfn) c\u00f3 nh\u1eefng v\u1ecb tr\u00ed li\u00ean k\u1ebft hidr\u00f4 b\u1ecb thay \u0111\u1ed5i l\u00e0m cho ch\u00fang k\u1ebft c\u1eb7p kh\u00f4ng \u0111\u00fang trong t\u00e1i b\u1ea3n (k\u1ebft c\u1eb7p kh\u00f4ng h\u1ee3p \u0111\u00f4i) d\u1eabn \u0111\u1ebfn ph\u00e1t sinh \u0111\u1ed9t bi\u1ebfn gen. V\u00ed d\u1ee5, guanin da\u0323ng hi\u00ea\u0301m (G*) k\u1ebft c\u1eb7p v\u1edbi timin trong t\u00e1i b\u1ea3n t\u1ea1o n\u00ean \u0111\u1ed9t bi\u1ebfn G \u2013 X \u2192 T \u2013 A<\/p>\n
* T\u00e1c \u0111\u1ed9ng c\u1ee7a c\u00e1c t\u00e1c nh\u00e2n g\u00e2y \u0111\u1ed9t bi\u1ebfn.<\/p>\n
– T\u00e1c \u0111\u1ed9ng c\u1ee7a c\u00e1c t\u00e1c nh\u00e2n v\u1eadt l\u00ed nh\u01b0 tia t\u1eed ngo\u1ea1i. (UV) c\u00f3 th\u1ec3 l\u00e0m cho hai baz\u01a1 timin tr\u00ean c\u00f9ng 1 m\u1ea1ch ADN li\u00ean k\u1ebft v\u1edbi nhau d\u1eabn \u0111\u1ebfn ph\u00e1t sinh \u0111\u1ed9t bi\u1ebfn gen.<\/p>\n
– T\u00e1c nh\u00e2n h\u00f3a h\u1ecdc nh\u01b0 5 \u2013 br\u00f4muraxin (5UB) l\u00e0 ch\u1ea5t \u0111\u1ed3ng \u0111\u1eb3ng c\u1ee7a timin g\u00e2y thay th\u1ebf A \u2013 T b\u1eb1ng G \u2013 X.<\/p>\n
– T\u00e1c nh\u00e2n sinh h\u1ecdc: d\u01b0\u1edbi t\u00e1c \u0111\u1ed9ng c\u1ee7a m\u1ed9t s\u1ed1 virut c\u0169ng g\u00e2y n\u00ean \u0111\u1ed9t bi\u1ebfn gen. V\u00ed d\u1ee5, virut vi\u00eam gan B, virut hecpet,\u2026<\/p>\n
B\u00e0i 3 (trang 22 SGK Sinh h\u1ecdc 12):\u00a0H\u1eadu qu\u1ea3 c\u1ee7a \u0111\u1ed9t bi\u1ebfn gen ph\u1ee5 thu\u1ed9c v\u00e0o nh\u1eefng y\u1ebfu t\u1ed1 n\u00e0o?<\/strong><\/p>\nL\u1eddi gi\u1ea3i:<\/strong><\/p>\nH\u1eadu qu\u1ea3 c\u1ee7a \u0111\u1ed9t bi\u1ebfn gen ph\u1ee5 thu\u1ed9c v\u00e0o c\u00e1c y\u1ebfu t\u1ed1 \u0111i\u1ec1u ki\u1ec7n m\u00f4i tr\u01b0\u1eddng v\u00e0 t\u1ed5 h\u1ee3p gen. Trong m\u00f4i tr\u01b0\u1eddng n\u00e0y ho\u1eb7c trong t\u1ed5 h\u1ee3p gen n\u00e0y th\u00ec alen \u0111\u1ed9t bi\u1ebfn c\u00f3 th\u1ec3 l\u00e0 c\u00f3 h\u1ea1i nh\u01b0ng trong m\u00f4i tr\u01b0\u1eddng kh\u00e1c ho\u1eb7c trong t\u1ed5 h\u1ee3p gen kh\u00e1c th\u00ec alen \u0111\u1ed9t bi\u1ebfn \u0111\u00f3 l\u1ea1i c\u00f3 th\u1ec3 c\u00f3 l\u1ee3i ho\u1eb7c trung t\u00ednh.<\/p>\n
\n
\n
B\u00e0i 4 (trang 22 SGK Sinh h\u1ecdc 12):\u00a0N\u00eau vai tr\u00f2 v\u00e0 \u00fd ngh\u0129a c\u1ee7a \u0111\u1ed9t bi\u1ebfn gen.<\/strong><\/p>\nL\u1eddi gi\u1ea3i:<\/b><\/p>\n
Vai tr\u00f2 v\u00e0 \u00fd ngh\u0129a c\u1ee7a \u0111\u1ed9t bi\u1ebfn gen:<\/p>\n
* \u0110\u1ed1i v\u1edbi ti\u1ebfn h\u00f3a:<\/p>\n
\u0110\u1ed9t bi\u1ebfn gen l\u00e0m xu\u1ea5t hi\u1ec7n c\u00e1c alen kh\u00e1c nhau cung c\u1ea5p nguy\u00ean li\u1ec7u cho qu\u00e1 tr\u00ecnh ti\u1ebfn h\u00f3a c\u1ee7a sinh v\u1eadt t\u1ea1o n\u00ean ngu\u1ed3n bi\u1ebfn d\u1ecb di truy\u1ec1n ch\u1ee7 y\u1ebfu cho qu\u00e1 tr\u00ecnh ti\u1ebfn h\u00f3a.<\/p>\n
* \u0110\u1ed1i v\u1edbi th\u1ef1c ti\u1ec5n:<\/p>\n
\u0110\u1ed9t bi\u1ebfn gen c\u0169ng cung c\u1ea5p nguy\u00ean li\u1ec7u cho qu\u00e1 tr\u00ecnh t\u1ea1o gi\u1ed1ng. V\u00ec v\u1eady, \u1edf m\u1ed9t s\u1ed1 \u0111\u1ed1i t\u01b0\u1ee3ng nh\u01b0 vi sinh v\u1eadt v\u00e0 th\u1ef1c v\u1eadt, c\u00e1c nh\u00e0 khoa h\u1ecdc th\u01b0\u1eddng ch\u1ee7 \u0111\u1ed9ng s\u1eed d\u1ee5ng c\u00e1c t\u00e1c nh\u00e2n \u0111\u1ed9t bi\u1ebfn \u0111\u1ec3 t\u1ea1o ra c\u00e1c gi\u1ed1ng m\u1edbi.<\/p>\n
B\u00e0i 5 (trang 22 SGK Sinh h\u1ecdc 12):\u00a0H\u00e3y ch\u1ecdn c\u00e2u \u0111\u00fang trong s\u1ed1 c\u00e1c c\u00e2u sau \u0111\u00e2y n\u00f3i v\u1ec1 \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m.<\/strong><\/p>\n\u00a0a) Trong s\u1ed1 c\u00e1c lo\u1ea1i \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m th\u00ec ph\u1ea7n l\u1edbn \u0111\u1ed9t bi\u1ebfn thay th\u1ebf c\u1eb7p nucleotit l\u00e0 \u00edt g\u00e2y h\u1ea1i nh\u1ea5t.<\/strong><\/p>\nb) \u0110\u1ed9t bi\u1ebfn \u0111i\u1ec3m l\u00e0 nh\u1eefng bi\u1ebfn \u0111\u1ed5i \u0111\u1ed3ng th\u1eddi t\u1ea1i nhi\u1ec1u \u0111i\u1ec3m kh\u00e1c nhau trong gen.<\/strong><\/p>\n\u00a0\u00a0c) Trong b\u1ea5t c\u1ee9 tr\u01b0\u1eddng h\u1ee3p n\u00e0o, tuy\u1ec7t \u0111\u1ea1i \u0111a s\u1ed1 \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m l\u00e0 c\u00f3 h\u1ea1i.<\/strong><\/p>\n\u00a0\u00a0d) \u0110\u1ed9t bi\u1ebfn \u0111i\u1ec3m l\u00e0 nh\u1eefng bi\u1ebfn \u0111\u1ed5i nh\u1ecf n\u00ean \u00edt c\u00f3 vai tr\u00f2 trong qu\u00e1 tr\u00ecnh ti\u1ebfn h\u00f3a.<\/strong><\/p>\nL\u1eddi gi\u1ea3i:<\/b><\/p>\n
\u0110\u00e1p \u00e1n: a.<\/p>\n
<\/p>\n<\/div>\n<\/div>\n
<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
B\u00e0i 1 (trang 22 SGK Sinh h\u1ecdc 12):\u00a0\u0110\u1ed9t bi\u1ebfn gen l\u00e0 g\u00ec? N\u00eau c\u00e1c d\u1ea1ng \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m th\u01b0\u1eddng g\u1eb7p v\u00e0 h\u1eadu qu\u1ea3 c\u1ee7a n\u00f3. L\u1eddi gi\u1ea3i: – Kh\u00e1i ni\u1ec7m \u0111\u1ed9t bi\u1ebfn gen: \u0110\u1ed9t bi\u1ebfn gen l\u00e0 nh\u1eefng bi\u1ebfn \u0111\u1ed5i trong c\u1ea5u tr\u00fac c\u1ee7a gen, c\u00f3 li\u00ean quan \u0111\u1ebfn m\u1ed9t ho\u1eb7c m\u1ed9t s\u1ed1 c\u1eb7p nucleotit. […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"tdm_status":"","tdm_grid_status":""},"categories":[1307],"tags":[1397,1398],"yoast_head":"\n
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N\u00eau c\u00e1c d\u1ea1ng \u0111\u1ed9t bi\u1ebfn \u0111i\u1ec3m th\u01b0\u1eddng g\u1eb7p v\u00e0 h\u1eadu qu\u1ea3 c\u1ee7a n\u00f3. L\u1eddi gi\u1ea3i: – Kh\u00e1i ni\u1ec7m \u0111\u1ed9t bi\u1ebfn gen: \u0110\u1ed9t bi\u1ebfn gen l\u00e0 nh\u1eefng bi\u1ebfn \u0111\u1ed5i trong c\u1ea5u tr\u00fac c\u1ee7a gen, c\u00f3 li\u00ean quan \u0111\u1ebfn m\u1ed9t ho\u1eb7c m\u1ed9t s\u1ed1 c\u1eb7p nucleotit. 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